In silico prediction of Gallibacterium anatis pan-immunogens
نویسندگان
چکیده
منابع مشابه
In silico prediction of Gallibacterium anatis pan-immunogens
The Gram-negative bacterium Gallibacterium anatis is a major cause of salpingitis and peritonitis in commercial egg-layers, leading to reduced egg production and increased mortality. Unfortunately, widespread multidrug resistance and antigenic diversity makes it difficult to control infections and novel prevention strategies are urgently needed. In this study, a pan-genomic reverse vaccinology ...
متن کاملNatural transformation of Gallibacterium anatis.
Gallibacterium anatis is a pathogen of poultry. Very little is known about its genetics and pathogenesis. To enable the study of gene function in G. anatis, we have established methods for transformation and targeted mutagenesis. The genus Gallibacterium belongs to the Pasteurellaceae, a group with several naturally transformable members, including Haemophilus influenzae. Bioinformatics analysi...
متن کاملGallibacterium anatis bacteremia in a human.
We describe the first case of bacteremia due to Gallibacterium anatis. The patient, a 26-year-old woman, developed bacteremia and diarrhea. The origin of infection was possibly due to a diet contaminated by G. anatis in this highly immunocompromised patient.
متن کاملDesigning a polytopic complex vaccine candidate against Gallibacterium anatis: an In-silico study
The haemolytic biovar of Gallibacterium anatis (G. anatis) is responsible for urogenital, gastrointestinal, and respiratory diseases in chickens. There are numerous reports on the resistance of G. anatis to antibiotics and recurrence of the disease, which raise concerns about antimicrobial treatment efficiency. Vaccination has been considered as the most feasibl...
متن کاملGenetic diversity of Gallibacterium anatis isolates from different chicken flocks.
Amplified fragment length polymorphisms (AFLPs) were used to characterize the genotypic diversity of a total of 114 Gallibacterium anatis isolates originating from a reference collection representing 15 biovars from four countries and isolates obtained from tracheal and cloacal swab samples of chickens from an organic, egg-producing flock and a layer parent flock. A subset of strains was also c...
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ژورنال
عنوان ژورنال: Veterinary Research
سال: 2014
ISSN: 1297-9716
DOI: 10.1186/s13567-014-0080-0